Xanthine Oxidase Inhibitor
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Potassium oxonate (Standard)
0 ImagesSynonyms: Potassium azaorotate (Standard); Potassium otastat (Standard); Oteracil potassium (Standard)Potassium oxonate (Standard) is the analytical standard of Potassium oxonate (HY-17511). This product is intended for research and analytical applications. Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate.
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Neosakuranin
0 ImagesCat. No.: HY-N17699CAS No.: 31187-54-9Neosakuranin is a flavonoid. Neosakuranin can be isolated from Sorbus commixta and the bark of P. cerasus. Neosakuranin exhibits suppressive effects on xanthine oxidase with an IC50 of 157.8 μM. Neosakuranin inhibits COX-l. Neosakuranin can be used in the research of inflammatory diseases.
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Topiroxostat (Standard)
0 ImagesSynonyms: FYX-051 (Standard)Topiroxostat (Standard) is the analytical standard of Topiroxostat. This product is intended for research and analytical applications. Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment.
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BOF-4272
0 ImagesCat. No.: HY-19164CAS No.: 142181-44-0BOF-4272 is a xanthine oxidase/xanthine dehydrogenase inhibitor. BOF-4272 can be used for hyperuricemia research.
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Hydroxyakalone
0 ImagesCat. No.: HY-N14777CAS No.: 182056-35-5Hydroxyakalone is an inhibitor of Xanthosine oxidase (XOD, EC 1.2.3.2), with an IC50 of 4.6 μM.
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Amflutizole
0 ImagesCat. No.: HY-119955CAS No.: 82114-19-0Synonyms: LY-141894Amflutizole (LY-141894) is an inhibitor of xanthine oxidase. Amflutizole abolishes free radical formation and release in cerebral ischemia/reperfusion mice.
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Xanthine oxidase-IN-14
0 ImagesCat. No.: HY-W560574CAS No.: 80025-67-8Xanthine oxidase-IN-14 (Compound 3f) is an inhibitor for xanthine oxidase, with IC50 >100 μM. Xanthine oxidase-IN-14 inhibits proliferations of cancer cells MCF-7, NCI-H460 and SF-268, with IC50 greater than 150 μM.
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Oxypurinol-13C,15N2-1
0 ImagesCat. No.: HY-W777649CAS No.: 1217036-71-9Synonyms: Oxipurinol-13C,15N2-1Oxypurinol-13C,15N2-1 (Oxipurinol-13C,15N2-1) is 15N and 13C labeled Oxypurinol (HY-19657). Oxipurinol, the major active metabolite of Allopurinoll (HY-B0219), is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.
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Xanthine oxidase-IN-22
0 ImagesCat. No.: HY-181095CAS No.: 3075445-37-0Xanthine oxidase-IN-22 is an orally active inhibitor of xanthine oxidase (XO) (IC50: 0.0034 μM). Xanthine oxidase-IN-22 exhibits a mixed-type inhibition mode against XO. Xanthine oxidase-IN-22 reduces serum uric acid levels in mice. Xanthine oxidase-IN-22 can be used in research related to hyperuricemia and gout.
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Nequinate (Standard)
0 ImagesCat. No.: HY-116433RCAS No.: 13997-19-8Nequinate (Standard) is the analytical standard of Nequinate. This product is intended for research and analytical applications. Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
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4-Nitrocinnamic acid (Standard)
0 ImagesCat. No.: HY-W015069RCAS No.: 619-89-64-Nitrocinnamic acid (Standard) is the analytical standard of 4-Nitrocinnamic acid (HY-W015069). This product is intended for research and analytical applications. 4-Nitrocinnamic acid is a Phenylpropanoids product that can be isolated from the heartwoods of Cassia garrettiana.
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5,6,7-Trihydroxy-4'-methoxyflavone
0 Images5,6,7-Trihydroxy-4'-methoxyflavone (4'-O-Methylscutellarein) is a flavonoid and a weak inhibitor of xanthine oxidase. 5,6,7-Trihydroxy-4'-methoxyflavone possesses antithrombotic and antioxidant activities. 5,6,7-Trihydroxy-4'-methoxyflavone has an IC50 value of 25.29 µM for DPPH free radical scavenging. 5,6,7-Trihydroxy-4'-methoxyflavone can also inhibit H2O2-induced damage to PC12 cells. 5,6,7-Trihydroxy-4'-methoxyflavone is applicable for the research of diseases such as cerebrovascular disorders.
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Digallic acid
0 ImagesDigallic acid is an antioxidant, antimutagenic, antigenotoxic, and anti-hyperuricemic compound. Digallic acid is a reverse transcriptase and XOD, URAT1 (IC50: 5.34 μM) inhibitor. Digallic acid scavenges DPPH· and O2·− radicals. Digallic acid induces apoptosis. Digallic acid can be isolated from the fruits of Pistascia lentiscus.
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Azapropazone (Standard)
0 ImagesCat. No.: HY-116442RCAS No.: 13539-59-8Azapropazone (Standard) is the analytical standard of Azapropazone (HY-116442). This product is intended for research and analytical applications. Azapropazone is an orally active nonsteroidal anti-inflammatory agent. Azapropazone inhibits Xanthine oxidase activity with an IC50 of 70-140 μg/mL. Azapropazone exerts significant cardiomyocyte protective effects on dogs with ischemia-reperfusion injury. Azapropazone reduces arthritis. Azapropazone inhibits Adrenaline-induced platelet aggregation. Azapropazone can be used for the research of myocardial ischemia and reperfusion injury, adjuvant arthritis, and gouty arthritis.
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Xanthine oxidase-IN-1
0 ImagesCat. No.: HY-U00288CAS No.: 1071970-13-2Synonyms: 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acidXanthine oxidase-IN-1 is a xanthine oxidase inhibitor extracted from patent WO2008126898A1, page 68, compound example 3, with an IC50 of 6.5 nM.
